超尔星学雅习通医学生物化学与分子生物学（17版）-成人教育作业参考答案

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2024 年秋季广东开放大学成人学历招生说明

医学生物化学与分子生物学（17版）_-成人教育

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问题: 1. Select the one FALSE statement:

选项:

• A. Marfan syndrome is due to mutations in the gene encoding fibrillin-1, a major constituent of microfibrils.

• B. All cases of Ehlers–Danlos syndrome are due to mutations affecting the genes encoding the various types of collagen.

• C. Laminin is found in renal glomeruli along with entactin, type IV collagen, and heparin or heparan sulfate.

• D. Mutations affecting type IV collagen can cause serious renal disease.

• E. Mutations in the collagen 1A1 gene can cause osteogenesis imperfecta.

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问题: 2. Regarding the ABO blood group substances, select the one FALSE statement:

选项:

• A. They can be either glycosphingolipids or glycoproteins, depending on location.

• B. Individuals with blood group AB have antibodies to both A and B blood group substances.

• C. Blood group H substance is formed from its precursor by the action of a fucosyltransferase.

• D. Blood group B is formed from its precursor by the action of a galactosyltransferase.

• E. Individuals of blood group O lack the galactosyltransferase.

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问题: 3. A male infant is failing to thrive and, on examination, is noted to have hepatomegaly and splenomegaly, among other findings. Urinalysis reveals the presence of both dermatan sulfate and heparan sulfate. You suspect the patient has Hurler syndrome. From the following list, select the enzyme that you would wish to have assayed to support your diagnosis:

选项:

• A. -Glucuronidase.

• B. -Galactosidase.

• C. -L-Iduronidase

• D. -N-Acetylglucosaminidase

• E. Neuraminidase

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问题: 4. 鞘糖脂的分子组成包括：

选项:

• A. 甘油

• B. 鞘氨醇

• C. 磷酸

• D. 糖链

• E. 脂肪酸

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问题: 5. 体内重要的糖胺聚糖有：

选项:

• A. 硫酸软骨素

• B. 硫酸角质素

• C. 肝素

• D. 硫酸皮肤素

• E. 透明质酸

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问题: 6. 以下说法正确的是：

选项:

• A. 糖蛋白和蛋白聚糖都是由糖与蛋白质两部分由共价键连接组成。

• B. 组成蛋白聚糖的糖链称为糖胺聚糖

• C. 组成糖蛋白的糖链可分为N-糖链和O-糖链

• D. 一般来说，糖蛋白分子中的蛋白质百分比小于糖，而蛋白聚糖则相反

• E. 组成糖蛋白和蛋白聚糖中的糖链结构迥然不同，功能也有差异

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